Funksjonell magnetresonansavbildning (fMRI) av hjernen; prinsipper og klinisk anvendelse

Research Area: Research Year: 2008
Type of Publication: Article
Authors: Hugdahl, Kenneth; Korsnes, M S; Specht, Karsten
Abstract:
In this article the authors describe how functional magnetic resonance imaging (fMRI) can be applied to brain activation related to cognitive processing. The physical and physiological principles behind fMRI are explained, as well as the principles behind analysis, visualisation and interpretation of fMRI data. The authors discuss issues related to spatial and temporal resolution in fMRI registration, and how fMRI responses are related to underlying neuronal activity and metabolism. A brief historical review on the use of fMRI in Norway is presented, with special emphasis upon the application of fMRI in the fields of neuropsychology and psychiatry. Examples are presented that illustrate how fMRI can be used to investigate auditory hallucinations in schizophrenia and epilepsy. The authors also explain how fMRI can contribute to the understanding of neuronal foundation for language processing and brain lateralization, with application to dyslexia. Examples from both national and international research are presented.
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