Transcranial brain stimulation and its underlying neural mechanism

The project, "Stopp Stemmer" wants to find out whether transcranial direct current stimulation (tDCS) can be used to reduce auditory hallucinations in patients with schizophrenia who do not respond to antipsychotic medication. tDCS uses only very weak electrical stimulation, so weak that many participants undergoing tDCS do not even notice it or only experience a tingling sensation. Yet, tDCS can inhibit or facilitate neural activity in specific brain regions. We hope that by inhibiting overly active speech areas and, at the same time, by boosting attention and control areas, the auditory hallucinations can be reduced. To examine the underlying neural mechanisms we additionally employ structural and functional neuroimaging before, after, and during tDCS. The project is funded by the Bergens Forskningsstiftelse and the University of Bergen.

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PI for the project is Marco Hirnstein, PhD