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New article

Neurophysiological evidence of impaired musical sound perception in cochlear-implant users, Clin Neurophysiol. 2010 Jun 4.

Sandmann P, Kegel A, Eichele T, Dillier N, Lai W, Bendixen A, Debener S, Jancke L, Meyer M.

Institute of Psychology, Division of Neuropsychology, University of Zurich, Switzerland; Department of Psychology, Neuropsychology Lab, Carl von Ossietzky University of Oldenburg, Germany.

Abstract:

OBJECTIVE: Music perception with a cochlear implant (CI) can be unsatisfactory because current-day implants are primarily designed to enable speech discrimination. The present study aimed at evaluating electrophysiological correlates of musical sound perception in CI users to help achieve the long-term goal of improved restoration of hearing in those individuals. METHODS: Auditory discrimination accuracy in adult CI users (n=12) and matched normal-hearing controls (n=12) was measured by behavioral discrimination tasks and mismatch negativity (MMN) recordings. Discrimination profiles were obtained by using a set of clarinet sounds (original/vocoded) varying along different acoustic dimensions (frequency/intensity/duration) and deviation magnitudes (four levels). RESULTS: Behavioral results and MMN recordings revealed reduced auditory discrimination accuracy in CI users. An inverse relationship was found between MMN amplitudes and duration of profound deafness. CONCLUSIONS: CI users have difficulties in discriminating small changes in the acoustic properties of musical sounds. The recently developed multi-feature MMN paradigm (Pakarinen et al., 2007) can be used to objectively evaluate discrimination abilities of CI users for musical sounds. SIGNIFICANCE: Measuring auditory discrimination functions by means of a multi-feature MMN paradigm could be of substantial clinical value by providing a comprehensive profile of the extent of restored hearing in CI users. Copyright © 2010 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

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New article

Maladaptation of event-related EEG responses preceding performance errors. Frontiers in Human Neuroscience. 2010.

Eichele, Heike; Juvodden, Hilde; Ullsperger, Markus; Eichele, Tom

Institute of Psychology, Division of Neuropsychology, University of Zurich, Switzerland; Department of Psychology, Neuropsychology Lab, Carl von Ossietzky University of Oldenburg, Germany.

Abstract:

Recent EEG and fMRI evidence suggests that behavioral errors are foreshadowed by systematic changes in brain activity preceding the outcome by seconds. In order to further characterize this type of error precursor activity, we investigated single-trial event-related EEG activity from 70 participants performing a modified Eriksen flanker task, in particular focusing on the trial-bytrial dynamics of a fronto-central independent component that previously has been associated with error and feedback processing. The stimulus-locked peaks in the N2 and P3 latency range in the event-related averages showed expected compatibility and error-related modulations. In addition, a small pre-stimulus negative slow wave was present at erroneous trials. Significant error-preceding activity was found in local stimulus sequences with decreased conflict in the form of less negativity at the N2 latency (310–350 ms) accumulating across five trials before errors; concomitantly response times were speeding across trials. These results illustrate that error-preceding activity in event-related EEG is associated with the performance monitoring system and we conclude that the dynamics of performance monitoring contribute to the generation of error-prone states in addition to the more remote and indirect effects in ongoing activity such as posterior alpha power in EEG and default mode drifts in fMRI.

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New Neuroscience book release

Simultaneous EEG and fMRI. Recording, Analysis and Application

Edited by Markus Ullsperger and Stefan Debener

Book Simultaneous EEG&fMRI
Click here for more information

 
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